声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较

郑剑; 吴曼丽; 王青娟; 王进芬; 张敏; 彭翔; 姚小虹; 郑荣琴

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声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较

临床研究 | 更新时间：2023-11-01

- 声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较
- Liver Stiffness Assessment by Sound Touch Elastography versus Two-dimensional Shear Wave Elastography: a Comparative Study
- 中山大学学报（医学科学版） 2020年41卷第4期页码：644-648
- 作者机构：
  
  1.深圳市龙岗区第三人民医院超声科，广东深圳 518115
  2.深圳市龙岗区人民医院超声科，广东深圳518115
  3.中山大学附属第三医院超声科，广东广州510630
- 作者简介：
  
  郑剑，博士研究生，副主任医师，研究方向：腹部浅表超声诊断与介入治疗、肝纤维化无创评估，E-mail：zhengj58@mail2.sysu.edu.cn
- 基金信息：
  
  广东省基础与应用基础研究基金(2019A1515011403)
- DOI：
  中图分类号： R445.1
- 纸质出版日期：2020-07-15，
  
  收稿日期：2020-02-17，
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郑剑,吴曼丽,王青娟等.声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较[J].中山大学学报（医学科学版）,2020,41(04):644-648.

ZHENG Jian,WU Man-li,WANG Qing-juan,et al.Liver Stiffness Assessment by Sound Touch Elastography versus Two-dimensional Shear Wave Elastography: a Comparative Study[J].Journal of Sun Yat-sen University(Medical Sciences),2020,41(04):644-648.
郑剑,吴曼丽,王青娟等.声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较[J].中山大学学报（医学科学版）,2020,41(04):644-648. DOI：

ZHENG Jian,WU Man-li,WANG Qing-juan,et al.Liver Stiffness Assessment by Sound Touch Elastography versus Two-dimensional Shear Wave Elastography: a Comparative Study[J].Journal of Sun Yat-sen University(Medical Sciences),2020,41(04):644-648. DOI：

摘要

目的

将声触诊弹性成像（STE）和二维剪切波弹性成像（2D-SWE）检测肝脏硬度进行比较，为STE新技术的临床应用提供循证依据。

方法

采用 STE和2D-SWE技术，对43例健康志愿者和63例肝硬化患者行肝硬度检测，对比分析两种技术的检测成功率、操作者内重复性、测值相关性和测值差异。

结果

肝脏STE、2D-SWE检测成功率分别为100%（106/106）、96.2%（102/106）（

=2.320，

=0.128），4例2D-SWE检测失败的均为肝硬化患者。在健康组STE测值高于2D-SWE[5.83(5.30~6.37) kPa

5.00(4.80~5.20) kPa，

=4.419，

0.001]、肝硬化组低于2D-SWE [15.82(11.71~25.02) kPa

18.50(11.95~29.93) kPa，

=-2.981，

=0.003]。STE和2D-SWE两种技术的测值相关系数为0.896（95%CI：0.849~0.928，

0.001）。

结论

STE检测成功率高、重复性好，尤其在肝硬化患者穿透性好、与2D-SWE比较更具优势；STE测值与2D-SWE不直接等同，临床应用中需要注意。

Abstract

Objective

To compare sound touch elastography (STE)

a new technique for the measurement of liver stiffness

and two-dimensional shear wave elastography (2D-SWE)

and to provide an evidence base for STE’s clinical practice.

Methods

The study included forty-three healthy volunteers and sixty-three patients with liver cirrhosis

in which liver stiffness was measured by means of STE and 2D-SWE. We compared the technical success rate

intra-operator reproducibility and liver stiffness values.

Results

The success rates of STE and 2D-SWE were 100% (106/106) and 96.2% (102/106)

respectively (

=2.320，

=0.128)

with four 2D-SWE examination failures in four patients with liver cirrhosis. Compared with those assessed by 2D-SWE

liver stiffness values assessed by STE were higher [5.83 (5.30~6.37) kPa

vs.

5.00 (4.80~5.20) kPa

=4.419

0.001] in the healthy group

but lower [15.82 (11.71~25.02) kPa

vs.

18.50 (11.95~29.93) kPa

=-2.981

=0.003] in the liver cirrhosis group. The Spearman′s rank correlation coefficient of STE and 2D-SWE was 0.896 (95%CI：0.849~0.928，

0.001).

Conclusion

With equally good reproducibility

STE is superior to 2D-SWE due to its higher success rate and better penetration especially in patients with cirrhosis. The liver stiffness values assessed by STE and 2D-SWE are not equivalent

which deserves our special attention in clinical application.

关键词

声触诊弹性成像二维剪切波弹性成像肝脏硬度肝硬化

Keywords

sound touch elastography (STE)two-dimensional shear wave elastography (2D-SWE)liver stiffnessliver cirrhosis

references

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