1.中山大学公共卫生学院,广东 广州 510080
2.中山大学附属第一医院手术室,广东 广州 510080
陈小俊,硕士研究生,研究方向:围术期妇幼保健,E-mail: chenxj88@mail.sysu.edu.cn
收稿:2020-08-23,
纸质出版:2021-01-20
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陈小俊,廖冰野,林梦伊等.高龄经产妇剖宫产术中出血风险因素分析[J].中山大学学报(医学科学版),2021,42(01):133-138.
CHEN Xiao-jun,LIAO Bing-ye,LIN Meng-yi,et al.Analysis of Risk Factors of Hemorrhage During Cesarean Section in Multiparous Women with Advanced Delivery Age[J].Journal of Sun Yat-sen University(Medical Sciences),2021,42(01):133-138.
陈小俊,廖冰野,林梦伊等.高龄经产妇剖宫产术中出血风险因素分析[J].中山大学学报(医学科学版),2021,42(01):133-138. DOI:
CHEN Xiao-jun,LIAO Bing-ye,LIN Meng-yi,et al.Analysis of Risk Factors of Hemorrhage During Cesarean Section in Multiparous Women with Advanced Delivery Age[J].Journal of Sun Yat-sen University(Medical Sciences),2021,42(01):133-138. DOI:
目的
2
分析高龄经产妇剖宫产术中出血风险因素,为防治剖宫产术中出血提供理论依据。
方法
2
回顾分析2015年1月至2019年12月在中山大学附属第一医院高龄经产妇剖宫产1 838例临床资料。根据产妇术中出血量是否≥500 mL,分为出血组与常规出血组,分析产妇基本资料、术中因素、胎盘因素等各类因素与术中出血相关性,通过多因素二分类Logistic回归分析得出独立风险因素。
结果
2
Logistic回归分析显示,手术时间[OR=1.069,95% CI为(1.050, 1.089),
P
<
0.001]、胎盘娩出方式[OR=3.131,95%CI为(1.259, 7.782),
P
=0.014]、胎儿窘迫[OR=4.727,95%CI为(1.191, 18.763),
P
=0.027]、手术级别[OR=21.494,95%CI为(6.031, 76.611),
P
<
0.001]、麻醉方式[OR=2.904,95%CI为(1.158, 7.281),
P
=0.023]和宫缩乏力[OR=7.255,95%CI为(4.413, 11.927),
P
<
0.001]为术中出血独立风险因素。
结论
2
手术时间、胎儿窘迫、手术级别、麻醉方式、宫缩乏力、胎盘娩出方式是高龄经产妇剖宫产术中出血主要影响因素,临床应针对以上风险因素,制定相应措施,以减低剖宫产术中出血风险。
Objective
2
To analyze the risk factors of hemorrhage during cesarean section in multiparous women with advanced delivery age, and provide a theoretical basis for the prevention and treatment of hemorrhage during cesarean section.
Methods
2
We retrospectively analyzed the clinical data of 1 838 women with advanced maternal age undergoing cesarean section in the First Affiliated Hospital of Sun Yat-sen University from January 2015 to December 2019. According to whether the intraoperative blood loss of the parturient is ≥ 500 mL, they were divided into hemorrhage group and non-hemorrhage group. The correlations of various factors such as basic maternal data, intraoperative factors, placental factors and intraoperative hemorrhage, and obtain the results by multi-factor binary logistic regression analysis independent risk factors were analyzed.
Results
2
Logistic regression analysis showed that operation time [OR=1.069, 95% CI: (1.050, 1.089),
P
<
0.001], placenta delivery method [OR=3.131, 95%CI: (1.259, 7.782),
P=
0.014], fetal distress [OR=4.727, 95% CI: (1.191, 18.763),
P
=0.027], surgical grade [OR=21.494, 95%CI: (6.031, 76.611),
P
<
0.001], anesthesia method [OR=2.904, 95%CI: (1.158, 7.281),
P
=0.023] and weak uterine contractions [OR=7.255, 95%CI: (4.413, 11.927),
P
<
0.001] were independent risk factors for intraoperative hemorrhage.
Conclusions
2
Operation time, fetal distress, operation level, anesthesia, uterine weakness, and placental delivery are the main influencing factors for bleeding during cesarean section in elderly women who have undergone cesarean section. Clinical measures should be taken to reduce the risk of hemorrhage during cesarean section.
王娟娟 , 朱建华 . 危重孕产妇治疗的现状与思考 [J]. 现代实用医学 , 2018 , 30 ( 4 ): 426 - 427, 430 .
Wang JJ , Zhu JH . Current status and thinking on treatment of critically ill pregnant women [J]. Modern Pract Med , 2018 , 30 ( 4 ): 426 - 427, 430 .
Rai V , Shariffuddin II , Chan YK , et al . Peri-operative management of hysterostomy in a parturient with complete heart block, placenta accreta and intrauterine death [J]. BMC Anesthesiol , 2014 , 14 : 49 .
Li Q , Deng D . New medical risks affecting obstetrics after implementation of the two-child policy in China [J]. Front Med , 2017 , 11 ( 4 ): 570 - 575 .
Ma Y , Shao M , Shao X . Analysis of risk factors for intraoperative hemorrhage of cesarean scar pregnancy [J]. Medicine (Baltimore) , 2017 , 96 ( 25 ): e7327 .
Saad A , Costantine MM . Obstetric hemorrhage: recent advances [J]. Clin Obstet Gynecol , 2014 , 57 ( 4 ): 791 - 796 .
Kolas T , Oian P , Skjeldestad FE . Risks for peri-operative excessive blood loss in cesarean delivery [J]. Acta Obstet Gynecol Scand , 2010 , 89 ( 5 ): 658 - 663 .
Rydahl E , Declercq E , Juhl M , et al . Cesarean section on a rise-does advanced maternal age explain the increase? A population register-based study [J]. PLoS One , 2019 , 14 ( 1 ): e210655 .
Frederiksen LE , Ernst A , Brix N , et al . Risk of Adverse Pregnancy Outcomes at Advanced Maternal Age [J]. Obstet Gynecol , 2018 , 131 ( 3 ): 457 - 463 .
Leader J , Bajwa A , Lanes A , et al . The effect of very advanced maternal age on maternal and neonatal outcomes: a systematic review [J]. J Obstet Gynaecol Can , 2018 , 40 ( 9 ): 1208 - 1218 .
Chen Y , Zheng XL , Wu SW , et al . Clinic characteristics of women with advanced maternal age and perinatal outcomes [J]. Zhonghua Fu Chan Ke Za Zhi , 2017 , 52 ( 8 ): 508 - 513 .
Ryu JM , Choi YS , Bae JY . Bleeding control using intrauterine continuous running suture during cesarean section in pregnant women with placenta previa [J]. Arch Gynecol Obstet , 2019 , 299 ( 1 ): 135 - 139 .
Yapca OE , Topdagi YE , Al RA . Fetus delivery time in extraperitoneal versus transperitoneal cesarean section: a randomized trial [J]. J Matern Fetal Neonatal Med , 2020 , 33 ( 4 ): 657 - 663 .
Chao YS , Mccormack S . Carbetocin for the prevention of post-partum hemorrhage: a review of clinical effectiveness, cost-effectiveness, and guidelines [M]. Ottawa (ON) : Canadian Agency for Drugs and Technologies in Health , 2019 .
Bullens LM , Smith JS , Truijens S , et al . Maternal hemoglobin level and its relation to fetal distress, mode of delivery, and short-term neonatal outcome: a retrospective cohort study [J]. J Matern Fetal Neonatal Med , 2020 , 33 ( 20 ): 3418 - 3424 .
Kim ML , Hur YM , Ryu H , et al . Clinical outcomes of prophylactic compression sutures for treatment of uterine atony during the cesarean delivery of twins [J]. BMC Pregnancy Childbirth , 2020 , 20 ( 1 ): 40 .
Fernandes NL , Dyer RA . Anesthesia for urgent cesarean section [J]. Clin Perinatol , 2019 , 46 ( 4 ): 785 - 799 .
Kang HW , Kim WY , Jin SJ , et al . Clinical evaluation of anesthesia for high-risk cesarean section at a tertiary medical center: retrospective study for 8 years (2009-2016) [J]. J Int Med Res , 2019 , 47 ( 9 ): 4365 - 4373 .
Arora G , Sahni N . Anesthetic management of a patient with Sheehan's syndrome and twin pregnancy while undergoing a cesarean section [J]. J Postgrad Med , 2020 , 66 ( 1 ): 51 - 53 .
王马列 , 郑菊 , 祝彩霞 , 等 . 产科急症子宫切除术51例临床分析 [J]. 中山大学学报(医学科学版) , 2016 , 37 ( 5 ): 757 - 762 .
Wang ML , Zheng J , Zhu CX , et al . Clinical analysis of 51 cases of acute obstetric hysterectomy [J]. J Sun Yat-sen Univ (Med Sci) , 2016 , 37 ( 5 ): 757 - 762 .
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