【Objective】To investigate the etiology，clinical manifestation，treatment and prognosis of optic disc vas? culitis.【Method】Twenty-four eyes of 21 patients were enrolled in this retrospective study. Eye examinations，treatment， and effect were recorded.【Result】Six were male and 15 were female. The age was between 19 and 43 years old（average： 28.7±1.6）. 85.7% of the patients referred to the clinic with mild to moderate decreased vision. Edema of the optic disc can be seen in both types while tortuous veins can also be found in type 2. Similar characteristics were noticed in OCT，FFA， and etc. With a follow-up of 4.52±0.98 months after treatment （prednisone：initial dose 1.0-1.2 mg/kg），the BCVA of the affected eyes improved significantly.【Conclusion】Optic disc vasculitis is affected by autoimmune disorder，infection，hy? perlipidemia，and etc. Edema of the optic disc with/without tortuous veins and retinal hemorrhage can be noticed. Similar diseases should be excluded in avoidance of misdiagnosis. Systemic examination and complete solution should be per? formed. Glucocorticoid helps to improve the visual function. The application of anti-VEGF is effective in secondary macu? lar edema. However，the long-term efficacy is awaiting being confirmed.