Abstract: 【Objective】 This study aims to analyze uterine artery involvement and its related factors in the early cervical cancer

and to explore the safety of the preservation of uterine artery in radical hysterectomy and radical trachelectomy. 【Methods】 We collected the specimens of uterine artery in patients with early cervical cancer from September 2012 to March 2014

and had pathological examination on them to study the involvement and the related factors. The specimens of uterine arteries we collected were from their origin to the parts before corpus uteri branch and cervix uteri branch. All the uterine artery specimens were observed pathologically. Data was analyzed in SPSS 13.0 software. 【Result】 A total of 61 patients were included in the study

of which there were 35 patients receiving the traditional procedure and 26 patients receiving the modified procedure. Only 1 case was with uterine artery involvement. The rate of uterine artery involvement was 1.6%. And another 3 cases had positive lymph node next to uterine artery. The rate of metastasis of the lymph node next to uterine artery was 4.9%. The rate of uterine artery was 50% in the group with parametrial tissue involvement

higher than that (1.6%) in the group without parametrial tissue involvement. The rate of involvement of lymph node next to uterine artery in the group with other pelvic metastasis was 100%

higher than that (1.7%) in the group without metastasis. And the differences were statistically significant (P < 0.05).By univariate logistic regression analysis

Parametrial tissue involvement and other pelvic metastasis were significantly associated with the involvement of uterine artery and/or the lymph node next to it (P < 0.05). No relation between the total uterine artery involvement and each character had been found yet by multivariate logistic regression analysis. All the patients with involvement of uterine artery or lymph node next to uterine artery had 3 or more than 3 following characters at the same time: tumor size>2cm

lymph vascular space invasion(LVSI)

depth invasion > 1/2

positive pelvic lymph node

vaginal involvement

isthmus uteri involvement

late clinical stage (stage ⅡB). Patients with 3 or more than 3 above-mentioned factors at the same time had an significantly increased risk for involvement of uterine artery or lymph node next to uterine artery(P < 0.05). The more number of coexisting factors

the higher risk for the involvement. 【Conclusion】 1.The possibility of uterine artery involvement in early cervical cancer is very low. It is considerable for the early cervical cancer patient without obvious parametrial involvement to preserve the uterus artery and their branches in radical hysterectomy and for the fit patient to preserve the uterus artery in radical trachelectomy. 2. Early cervical cancer patients with 3 or more than 3 above-mentioned factors

who ask for surgical therapy

are suggested to have Piver Ⅲ type hysterectomy by the traditional method.