【Objective】 The project investigated clinical features of ocular ischemic syndrome (OIS) and the influence of hypertension on vision and fundus lesion. 【Method】 Retrospective analysis was performed on 124 patients of OIS. 【Results】 Mean age of all patients was 63.64 (S = 12.13)

with a ratio of 1.8∶1 between male and female. Among all patients

96.77% were detected carotid artery stenosis

mainly accompanied by hypertension

diabetes and cardiovascular and cerebrovascular disease. They presented with reduced visual acuity and amaurosis fugax

along with iris neovascularization at anterior segment and arteriostenosis

phlebectasia

dot and blot hemorrhage at retina by ophthalmoscope examination. Fundus fluorescein angiography (FFA) exhibited prolongation of arm-retina time and arteriovenous circulation time

microaneurysms and capillary non-perfusion region. And visual disturbance between normotensive and hypertensive patients showed significant difference (P < 0.01). 【Conclusion】 OIS

characterized as complicated clinical manifestations and deteriorated by hypertension

is mainly induced by carotid stenosis

commonly seen among aged population. Ophthalmoscope examination and FFA afford key methods for its early diagnosis with co-diagnosis and co-treatment from neurologist and cardiologist.