【Objective】To study the diagnostic value of computed tomography（CT）in the diagnosis of infantile congenital lung malformation（CLM）.【Methods】A total of 76 CLM patients diagnosed in the Third Affiliated Hospital of Guangzhou Medical University from May 2019 to May 2020 were selected. The diagnostic accuracy of preoperative CT and prenatal ultrasound（US）diagnosis of CLM was compared based on the gold standard of pathological results. The preopera⁃ tive CT findings and differential diagnosis were analyzed.【Results】Among the 76 cases of CLM，there were 36 cases of congenital pulmonary airway malformation（CPAM），26 cases of pulmonary sequestration（PS），8 cases of congenital lobar emphysema（CLE），and 6 cases of mixed type. There was a moderate agreement between CT and US diagnosis of CLM（Kappa = 0.465，P < 0.05）. The accuracy rate of CT diagnosis was 85.5%，which was higher than that of US（69.7%）. McNemar test result is P =0.001，the difference of diagnostic value between CT and US was statistically significant. In terms of CT manifestations，CPAM was mainly characterized by cystic lesions of different sizes. PS showed pulmonary mass with abnormal blood supply artery，mainly from the aortic branch. CLE was characterized by overexpansion of the pulmonary lobes and thinning of the pulmonary blood vessels.【Conclusions】In infantile CLM，preoperative CT is an im⁃ portant supplementary examination for prenatal US. Different types of CLM have different manifestations. CT can diagnose and distinguish different types of CLM，which provides an important basis for preoperative clinical evaluation.