中山大学附属第三医院心血管内科,广东 广州510630
刘可美,博士,住院医师,E-mail:liukm5@mail.sysu.edu.cn
收稿:2021-03-17,
纸质出版:2021-07-20
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刘可美,陈泽锋,税星等.酒精性心肌病合并心房颤动的临床特征及影响因素分析[J].中山大学学报(医学科学版),2021,42(04):635-640.
LIU Ke-mei,CHEN Ze-feng,SHUI Xing,et al.Atrial Fibrillation in Patients with Alcoholic Cardiomyopathy:Clinical Characteristics and Risk Factors[J].Journal of Sun Yat-sen University(Medical Sciences),2021,42(04):635-640.
刘可美,陈泽锋,税星等.酒精性心肌病合并心房颤动的临床特征及影响因素分析[J].中山大学学报(医学科学版),2021,42(04):635-640. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0421.
LIU Ke-mei,CHEN Ze-feng,SHUI Xing,et al.Atrial Fibrillation in Patients with Alcoholic Cardiomyopathy:Clinical Characteristics and Risk Factors[J].Journal of Sun Yat-sen University(Medical Sciences),2021,42(04):635-640. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0421.
目的
2
探讨酒精性心肌病(ACM)合并心房颤动(AF)的患者的临床特征,分析各特征与ACM患者发生AF的相关性。
方法
2
回顾性分析2013年1月至2020年4月期间于中山大学附属第三医院心血管内科住院的ACM患者42例及ACM合并AF(ACM-AF)患者17例为研究对象,收集患者的临床资料、实验室指标及超声心动图检查结果,比较其临床特征,并采用多因素Logistic回归分析研究ACM患者发生AF的相关影响因素。
结果
2
单因素分析显示,ACM-AF组与ACM组在年龄[(56.82±9.48)岁
vs.
(50.55±10.60)岁,
P
=0.038]、左心房内径[(48.29±8.76)mm
vs.
(44.38±5.03) mm,
P
=0.035] 和血肌酐值[80(73~95.45)μmol/L
vs.
98.5(84~108.25)μmol/L,
P
=0.032] 方面的差异具有统计学意义(
P
<0.05)。多因素Logistic回归分析发现,年龄和左心房内径与ACM患者发生AF相关,而血肌酐值不是影响ACM患者发生AF的相关因素。
结论
2
年龄和左心房内径是ACM患者发生AF的影响因素。
Objective
2
To explore the clinical characteristics of alcoholic cardiomyopathy (ACM) combined with atrial fibrillation (AF) and risk factors for AF in ACM patients.
Methods
2
A retrospective analysis was performed on 42 cases of ACM (ACM group) and 17 cases of ACM combined with AF (ACM-AF group) hospitalized in our hospital from January 2013 to April 2020. The clinical data, laboratory findings and echocardiographic results were compared between ACM group and ACM-AF group. Multivariate Logistic regression analysis was used to detect the risk factors for AF in ACM patients.
Results
2
Univariate analysis showed significant difference in age [(56.82±9.48)years
vs.
(50.55±10.60)years,
P
=0.038], left atrial diameter [(48.29±8.76) mm
vs.
(44.38±5.03) mm,
P
=0.035] and serum creatinine [80 (73~95.45) μmol/L
vs
. 98.5 (84~108.25) μmol/L,
P
=0.032] between ACM-AF group and ACM group (
P
<0.05). Multivariate Logistic regression analysis revealed that age and left atrial diameter were the influencing factors of AF in ACM patients (
P
<0.05), while serum creatinine has no effect on the incidence of AF in ACM patients (
P
>0.05).
Conclusion
2
The older age and enlarged left atrial diameter are the risk factors for AF in patients with ACM.
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