1.中山大学中山眼科中心眼科学国家重点实验室//广东省眼科视觉科学重点实验室,广东 广州 510060
2.中山爱尔眼科医院,广东 中山 528403
3.武汉大学附属爱尔眼科医院,湖北 武汉 430000
4.深圳市人民医院,广东 深圳 518000
黄洁蕾,硕士,主治医师,研究方向: 青光眼,E-mail:hjlei@mail2.sysu.edu.cn
收稿:2022-01-10,
纸质出版:2022-03-20
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黄洁蕾,陈翔熙,钟毅敏等.青少年型开角型青光眼滤过手术的长期临床疗效[J].中山大学学报(医学科学版),2022,43(02):316-320.
HUANG Jie-lei,CHEN Xiang-xi,ZHONG Yi-min,et al.Long Term Outcomes of Trabeculectomy in Juvenile Open Angle Glaucoma[J].Journal of Sun Yat-sen University(Medical Sciences),2022,43(02):316-320.
黄洁蕾,陈翔熙,钟毅敏等.青少年型开角型青光眼滤过手术的长期临床疗效[J].中山大学学报(医学科学版),2022,43(02):316-320. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0218.
HUANG Jie-lei,CHEN Xiang-xi,ZHONG Yi-min,et al.Long Term Outcomes of Trabeculectomy in Juvenile Open Angle Glaucoma[J].Journal of Sun Yat-sen University(Medical Sciences),2022,43(02):316-320. DOI: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0218.
目的
2
探讨青少年型开角型青光眼小梁切除术长期疗效。
方法
2
回顾性研究收集18岁以内接受小梁切除术联合丝裂霉素C(MMC)的青少年型开角型青光眼共31例55眼,比较手术前后眼压及其他眼部参数。
结果
2
所有患者术后眼压比术前明显降低(
t
=12.254,
P
<0.001),手术前后C/D值、眼轴长度、视野MD值、视力及屈光度无明显变化,术后第1、3、6年手术完全成功率分别为92.7%、70.4%、42.6%。手术条件成功率分别为92.7%、81.0%、81.0%。术中及术后未发生严重并发症。
结论
2
小梁切除术联合MMC是治疗青少年型开角型青光眼一种较为安全、成功率较高的手术方式。
Objective
2
To evaluate the long term efficacy of trabeculectomy in juvenile open angle glaucoma (JOAG).
Methods
2
A total of 55 eyes of 31 patients with JOAG, who underwent trabeculectomy within 18 years old were retrospectively studied. Pre- and post-operative IOPs and other parameters were evaluated.
Results
2
The post-op IOPs were significantly lower than that of pre-op IOPs(
t
=12.254,
P
<0.001). There was no significant change in C/D ratio, axial length, MD value of visual field, visual acuity and diopter before and after operation. The complete success rates for all eyes at 1, 3 and 6 years after operation were 92.7%, 70.4% and 42.6%, respectively. The conditional success rates were 92.7%, 81.0% and 81.0%, respectively. There were no severe intraoperative or post-op complications.
Conclusion
2
Trabeculectomy combined with MMC is a safe and successful method for the treatment of JOAG.
中华医学会眼科学分会青光眼学组 , 中国医师协会眼科医师分会青光眼学组 . 中国青光眼指南(2020年) [J]. 中华眼科杂志 , 2020 , 56 ( 8 ): 573 - 586 .
Glaucoma group of Chinese society of ophthalmology , glaucoma group of Chinese college of ophthalmologists . Chinese glaucoma guideline 2020 [J]. Chin J Ophthalmol , 2020 , 56 ( 8 ): 573 - 586 .
Selvan H , Gupta S , Wiggs JL , et al . Juvenile-onset open-angle glaucoma - a clinical and genetic update [J]. Surv Ophthalmol , 2021 , 5 : S0039-6257(21)00184 - 3 .
闻毅颐 , 李东豪 , 胡利 . 改良复合式小梁切除术治疗原发性闭角型青光眼的效果 [J]. 广东医学 , 2014 , 35 ( 7 ): 1083 - 1085 .
Wen YY , Li DH , Hu L , et , al . Effect of modified compound trabeculectomy for primary angle-closure glaucoma [J]. Guangdong Med J , 2014 , 35 ( 7 ): 1083 - 1085 .
蒋自培 , 胡赛静 , 孔丽萍 , 等 . 原发性开角型青光眼药物治疗后单次眼压达目标眼压的安全性——附37眼分析 [J]. 新医学 , 2009 , 40 ( 1 ): 39 - 41 .
Jiang ZP , Hu SJ , Kong LP , et al . Safety of a single IOP target after drug therapy for primary open-angle glaucoma-37 eye analysis [J]. J New Med , 2009 , 40 ( 1 ): 39 - 41 .
Fieß A , Furahini G , Bowman R , et al . Outcomes of surgical interventions for primary childhood glaucoma in Northern Tanzania [J]. Br J Ophthalmol , 2017 , 101 ( 2 ): 126 - 130 .
Papadopoulos M , Vanner EA , Grajewski AL ; International study of childhood glaucoma- childhood glaucoma research network study group . International study of childhood glaucoma [J]. Ophthalmol Glaucoma , 2020 , 3 ( 2 ): 145 - 157 .
Pathania D , Senthil S , Rao HL , et al . Outcomes of trabeculectomy in juvenile open angle glaucoma [J]. Indian J Ophthalmol , 2014 , 62 ( 2 ): 224 - 228 .
Nash DL , Crouch ER , Crouch ER , et al .. Comparison of EX-PRESS shunt and trabeculectomy with mitomycin-c in congenital and juvenile glaucoma [J]. J Glaucoma , 2017 , 26 ( 2 ): e58 - e63 .
Yalvac IS , Nurö , Zler A , et al . The results of trabeculectomy with and without mitomycin C in young patients [J]. Ophthalmologica , 1998 , 212 ( 6 ): 399 - 403 .
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