Correlation Between the Prevalence of HHcy，Blood Lipids and Uric Acid in the Tibetan Population in Northwest Xizang

XIAO Ruoyu; ZHANG Yufei; XIONG Hai

doi:10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240319.001

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Correlation Between the Prevalence of HHcy，Blood Lipids and Uric Acid in the Tibetan Population in Northwest Xizang

Clinical Research | 更新时间：2024-04-15

- Correlation Between the Prevalence of HHcy，Blood Lipids and Uric Acid in the Tibetan Population in Northwest Xizang
- Journal of Sun Yat-sen University(Medical Sciences) Vol. 45, Issue 2, Pages: 324-330(2024)
- 作者机构：
  
  1.中山大学医学院广东深圳518000
  2.西藏大学医学院西藏拉萨 850000
- 作者简介：
  
  XIONG Hai；E-mail：xhxysq@126.com
- 基金信息：
- DOI：10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240319.001
  CLC： R54
- Published：20 March 2024，
  
  Received：23 December 2023，
  
  Accepted：14 March 2024
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肖若愚,张玉飞,熊海.西藏西北地区藏族人群高同型半胱氨酸血症的患病现状与血尿酸血脂的关联性分析[J].中山大学学报（医学科学版）,2024,45(02):324-330.

XIAO Ruoyu,ZHANG Yufei,XIONG Hai.Correlation Between the Prevalence of HHcy，Blood Lipids and Uric Acid in the Tibetan Population in Northwest Xizang[J].Journal of Sun Yat-sen University(Medical Sciences),2024,45(02):324-330.
肖若愚,张玉飞,熊海.西藏西北地区藏族人群高同型半胱氨酸血症的患病现状与血尿酸血脂的关联性分析[J].中山大学学报（医学科学版）,2024,45(02):324-330. DOI： 10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240319.001.

XIAO Ruoyu,ZHANG Yufei,XIONG Hai.Correlation Between the Prevalence of HHcy，Blood Lipids and Uric Acid in the Tibetan Population in Northwest Xizang[J].Journal of Sun Yat-sen University(Medical Sciences),2024,45(02):324-330. DOI： 10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240319.001.

摘要

目的

为了了解西藏西北地区藏族人群高同型半胱氨酸血症（HHcy）患病现状及其与血脂、血尿酸等的关联，探讨西藏西北地区高同型半胱氨酸血症等慢性病的防治策略。

方法

本次调查采用多阶段分层整群随机抽样的方法，对西藏西北地区（阿里地区、那曲市）居住6个月以上、18岁及以上的3 432名藏族居民进行了问卷调查、体格检查以及生化检测等。

结果

西藏西北地区藏族居民HHcy患病率为75.7%，远高于我国平均人群的患病率（37.2%）。血尿酸、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇是HHcy的危险因素。

结论

西藏西北地区藏族人群的HHcy患病率高。当地政府应敦促人们建立健康的生活方式，通过改善饮食和生活方式，加强对HHcy的早期干预，降低心脑血管等相关疾病的发生风险。

Abstract

Objectives

To understand the prevalence of hyperhomocysteinemia （HHcy） in the Tibetan population in Northwest Xizang， and its association with lipids and blood uric acid， and to explore the prevention and treatment strategies for chronic diseases such as HHcy in Northwest Xizang.

Methods

In this survey， questionnaires， physical examinations， and biochemical tests were conducted on 3432 Tibetan residents aged 18 years and older who had resided in Northwest Xizang （Ngari Prefecture， Nagqu City） for more than 6 months using a multistage stratified whole cluster random sampling method.

Results

The prevalence of HHcy among Tibetan residents in Northwest Xizang was 75.7%， much higher than that of the average population in China （37.2%）. Blood uric acid、high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were risk factors for HHcy.

Conclusion

The prevalence of HHcy is higher in the Tibetan population in northwest Xizang. Therefore， the local governments should urge people to establish a healthy lifestyle and enhance early intervention for HHcy by improving diet and lifestyle， thereby reducing the risk of cardiovascular， cerebrovascular and other related diseases.

关键词

西藏西北地区高同型半胱氨酸血症血脂血尿酸关联性

Keywords

Northwest Xizanghyperhomocysteinemiablood lipidsblood uric acidassociation

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